Ebola fightback

 作者:郜缵嘉     |      日期:2019-03-08 06:20:00
SURVIVORS of the Ebola virus are helping researchers to develop a vaccine and treatment for the disease. The effects of Ebola on the immune system are poorly understood and until now no one has ever found antibodies that can bind the virus, which causes death by haemorrhaging. But Paul Parren of the Scripps Research Institute in La Jolla, California, and his colleagues examined messenger RNA from the survivors of a 1995 outbreak to identify all the antibodies that they produced. The team found one particular antibody that binds and neutralises Ebola, and this antibody protected guinea pigs against infection (Journal of Virology, vol 73, p 6024). The researchers now hope to test the antibody in primates and create a vaccine that stimulates its production. “It helps us in vaccine design,